The oxidized form of glutathione
نویسندگان
چکیده
منابع مشابه
Endoplasmic reticulum : Reduced and oxidized glutathione
6 Division of Molecular and Systems Toxicology, Department of Pharmaceutical 7 Sciences, University of Basel, 4056 Basel, Switzerland 8 2 Swiss Center for Applied Human Toxicology, University of Basel, 4056 Basel, 9 Switzerland 10 3 INRES – Chemical Signalling, University of Bonn, 53113 Bonn, Germany 11 4 Department of Biology, University of Copenhagen, 2200 Copenhagen N, Denmark 12 5 D...
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The reduced glutathione of normal and glucose-6-P dehydrogenase-deficient human erythrocytes was oxidized by subjecting the cells to HzOz diffusion or to treatment with methyl phenylazoformate. A portion of the oxidized glutathione thus formed disappeared from the erythrocytes and could be recovered from the medium when the normal cells were incubated in the absence of glucose or when glucose6-...
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Crude extracts of pea shoots (Pisum sativum) catalyzed oxidized glutathione (GSSG)-dependent oxidation of NADPH which was attributed to NADPH-specific glutathione reductase. The pH optimum was 8 and the K(m) values for GSSG and NADPH were 23 mum and 4.9 mum, respectively. Reduced glutathione (GSH) inhibited the reaction. Crude extracts also catalyzed NADPH-dependent reduction of GSSG; the ratio...
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To determine the role of free radical mechanisms in the pathogenesis of amyotrophic lateral sclerosis (ALS), cerebrospinal fluid concentrations of oxidized nitric oxide (NO) products (nitrite and nitrate) and reduced and oxidized forms of glutathione (GSH and GSSG, respectively) were compared between patients with the sporadic form of ALS (SALS) and controls. In the SALS patients, the nitrate l...
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Oxidized l-glutathione was esterified to the tetra methyl ester using thionyl chloride in methanol solvent. Other alcohols were tested and the reaction progress was monitored via ESI-MS. This procedure proved to be compatible with other small peptides not containing serine and cysteine residues. In contrast to previously reported methods this procedure provided convenient access to esterified p...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section C Crystal Structure Communications
سال: 1999
ISSN: 0108-2701
DOI: 10.1107/s0108270199007039